We all know the chaos caused by an energy crisis …. gas prices just came down. Knowing that good feeling we now have again when we fuel up. We all know the that feeling of being zapped by static electricity at times also. Or when Christmas light burn out and takes the whole strand right along with it. One small problem when it comes to health issues, it can also trigger a domino effect of lasting effects. This happens when you can’t sustain your energy levels. Which may lead to a short circuiting of your energy system.
Myths in science that refuse to die: How a seed of truth can grow into an unshakeable false belief.
You may think that your body isn’t wired electrical, but think again. As your heart beats about 100,000 times in one day and about 35 million times in a year. During an average lifetime, the human heart will also beat more than 2.5 billion times. Realizing this we realize the culprits to bad health maybe not enough sleep, to many calories, to much saturated fat and sugary foods, too much stress, not enough fun and enjoyment or passion in life.
Therefore, to see how energy levels dip, let’s look at how energy works. The energy in your body is stored in packets called ATP, as well as phosphocreatine. Which are made up of a number of chemicals including a sugar called ribose, adenine (which use to be called vitamin B4), and derivatives of B vitamins. What are inside your cells (nutrients and genes) and other substances that act likes swtiches and fuses to regulate this power factory within you.
Your mitochrondria, their component ribosomes take the ribose, sugar and B vitamin helpers and use electron transport to crank out ATP — your energy packets. Once you have enough ATP – your body can crank out activities. NOW if you blow the fuse that allows you to produce ATP — through infection, hormonal dysfunctions, not getting enough sleep, having a diet that diverts energy rather than stimulates it. Your body produces energy inefficiently, using all its energy to, well, produce and store energy.
Thereby, even though you have plenty of ATP — you also need abundant blood flow to provide the nutrients, take away “waste” products. This comes down to doing things that help keep your arteries dilated and your blood pumping. Therefore, what is good for your heart and arteries is good for your energy levels, too. For ex., nitric oxide — that short lived gas — that lines your arteries and breathing tubes and in your brain.
That’s rapidly changes according to your diet and activity levels and helps open up your arteries and lung passages to improve blood flow and increase the transfer of oxygen. Problems within these systems really contribute to energy deficiencies, yet the onset, cause, and treatments of lack of get – up – and – go are hard to diagnose. While fatigue, the lack of energy with the inability to sleep can explain other health problems.
The truth is when you put together, this constellation of symptoms. It makes it hard to navigate through the 4 distinct directions of life (North, South, East and West.) So what starts this process that steals your energy? What sets up this domino effect that makes your cellular energy plants — that ATP – those mitochrondia to become inefficient. Some health experts express it maybe:
https://www.youtube.com/watch?v=m9lz-0MiM6g
https://www.youtube.com/watch?v=vSP6QEn9NMA
Everyone in the modern world should take the time to hear this
http://youtu.be/DTMuOn2T1h4
The Science of Simple May be The Cause of Cancer!!!
Cancer starts when cells in a part of the body start to grow out of control. Cancer cell growth is different from normal cell growth. Instead of dying off, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells can’t do. Thereby, Growing out of control and invading other tissues are what makes a cell a cancer cell.
Cells become cancer cells because of changes to their DNA (deoxyribonucleic acid). DNA is in every cell and it directs all its actions. In a normal cell, when DNA is damaged the cell either repairs the damage or dies. In cancer cells, the damaged DNA is not repaired, but the cell doesn’t die like it should. Instead, the cell goes on making new cells that the body doesn’t need. These new cells all have the same damaged DNA as the first cell does.
People can inherit abnormal or faulty DNA (it’s passed on from their parents), but most DNA damage is caused by mistakes that happen while a normal cell is reproducing or by something in the environment. Sometimes DNA damage may be caused by something obvious like cigarette smoking or sun exposure. But it’s rare to know exactly what caused any one person’s cancer.
In most cases, the cancer cells form a tumor. Over time, the tumors can invade nearby normal tissue, crowd it out, or push it aside. Some cancers, like leukemia, rarely form tumors. Instead, these cancer cells involve the blood and blood-forming organs and circulate through other tissues where they grow.
Scientists have discovered a central mechanism in cancer cells, which helps speed up the growth of cancer cells. Cancer cells grow faster than the body’s own healthy cells. This is one of the reasons why the disease is able to spread so quickly around the body once it has gained a foothold.
Now scientists at the University of Copenhagen have identified a mechanism that helps explain why cancer cells grow so rapidly.
The mechanism is caused by a faulty placement of essential enzymes in the cancer cells, which causes changes in the proteins on the surface of the cancer cells. This mechanism plays a part in the growth of the cancer cells.
Although the new findings are still at a basic research level, one of the researchers behind the study believes that the mechanism may become a possible target in the fight against cancer:
“This places us in a good position in the fight against cancer. The moment you realise that a process plays an important part in the development of cancer, you can start to consider how you can influence the process so that the cancer cells cannot make use of it,” explains Professor Henrik Clausen, who heads the Copenhagen Center for Glycomics at the University of Copenhagen.
The study is published in the journal PNAS.
The Link Between Sugar and Cancer is IMPORTANT!!!
AGE’s: Clearing up kidney function!!!
1-It tends to be processed mainly by the liver, so it’s tough to get it out of circulation.
2-Fructose tends to alter liver function, contributing to insulin resistance.
3-Fructose is structurally more reactive than glucose. At any given concentration, we can expect fructose to produce more AGE’s relative to glucose.
4-Fructosse tends to be pro-inflammatory via actions on both the liver, and alterations in gut bacteria.
AGE’s are problematic for kidney function as they damage delicate structures such as the glomerlus, which can limit normal GFR. Damage to the distal portions of the nephron can alter reabsorption. The net result is that our ability to filter out toxic substances such as urea and or regulate normal fluid and electrolyte balance are dramatically altered.
Sugar boosts cancer growth!!!!
The researchers studied a special property of cancer cells that distinguishes them from healthy cells and have identified a possible mechanism behind shortened sugar molecules. They also discovered that when we made changes to the mechanism, we reduced the rapid growth of the cancer cells.
Scientists have known about this since the 1980s, and many attempts have since been made to use this special property in cancer cells to come up with ways of identifying cancer in the body.
The new study, carried out in collaboration with researchers from Singapore, reveals that the short sugar chains are not only a special characteristic of cancer cells; they are also involved in the rapid growth of the cancer cells.
The researchers also found how the cancer cells produce these short sugar chains:
“We have identified a possible mechanism behind the shortened sugar molecules,” says co-author Catharina Steentoft, a PhD student at the Copenhagen Center for Glycomics.
“We also discovered that when we made changes to the mechanism, we reduced the rapid growth of the cancer cells.”
Understanding the mechanism!!!
Here’s how the mechanism works:
- All cells contain enzymes that are involved in the formation of sugar molecules on the cell’s surface proteins. This process is known as glycosylation.
- In healthy cells, the enzymes are located in the part of the cell that’s known as the Golgi apparatus, which is a type of membrane system inside the cell. In cancer cells, however, the enzymes are located in another membrane system called the endoplasmic reticulum.
- When proteins are formed inside the cells, they pass through both of these membrane systems, where the enzymes attach sugar chains to the proteins before they are transported out to the cell’s surface.
There are, however, differences in how the enzymes attach sugar molecules to the proteins in the two membrane systems:
“The difference between glycosylation in cancer cells and in healthy cells is that the enzymes are located in different parts of the cell,” says Steentoft.
“This means that healthy cells have long, complex sugar chains attached to their surface proteins, while cancer cells get short and simple ones attached to their surface proteins.”
Why cancer cells grow so fast!!!
In the study, the researchers tested the mechanism and its effect on mice.
Having injected cancer cells into the mice, they observed that the mice that had been given cancer cells in which the enzymes in the endoplasmic reticulum were put out of action survived longer and had smaller and fewer tumours.
“This means that the repositioning of the enzymes from their original location in the Golgi apparatus to the endoplasmic reticulum somehow plays a role in cancer cell growth,” says Steentoft.
Study increases our understanding of cancer spreads !!!
The new findings provide the researchers with an insight into one of the characteristics of cancer cells that makes the disease so difficult to control.
The research is still at a very early basic research level, and Steentoft is reluctant to say when the new findings will be used in the fight against cancer, or whether the mechanism will even become a target for cancer treatment.
”Our findings increase our understanding of cancer. The newly-discovered mechanism is one of the possible explanations of why the sugar chains in cancer cells have the short structure and what this means for the growth of the cancer cells,” she says.
More evidence—if more was needed—that cancer feeds off sugar has come from two new studies.
In the first, researchers have found that people with high insulin levels—insulin is produced by the body to break down sugar in carbohydrates—have faster-growing tumours that spread. While in the second study, researchers have discovered that glucose, the sugar in our blood, plays a key role in the survival of cancer cells.
Although cancer specialists have known that high insulin levels contribute to the growth of tumours in women with early–stage breast cancer, researchers have discovered that excessive production of insulin. Which is the pre–diabetic stage brought on by a diet of high-sugar, processed carbohydrates from fast foods, cakes and biscuits—helps cancer spread (metastasize) and makes it more likely to be lethal.
Researchers from the Galliera Hospital in Genoa made the discovery when they profile 125 women with breast cancer that had spread. None of the women were diabetic, but nearly half were insulin-resistant—normal levels of insulin weren’t breaking down the sugar in foods—while 40 per cent were overweight and 16 per cent were obese.
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They discovered that those with high insulin levels were more likely to have a cancer that had spread, and they also had a higher chance of dying from their cancer.
In the second study, researchers have discovered the vital role that glucose plays in helping cancer cells communicate, thrive and grow. Glucose is taken from sugars in carbohydrates and is vital for life, but excessive amounts become food for cancer cells.
Researchers at Ohio State University have found that high levels of glucose in the blood play a key role when cancer cells start to form and grow. One area for research, they suggest, could be targeting the pathways that allow glucose to feed the cells.
”But I would also like to point out that they’re still very far from finding a cure.”