What We Know (and Don’t Know) About Alzheimer’s Disease.
Research has delivered only limited insights into causes and treatments.
by Kathleen Fifield, AARP.
Here’s what we know:
The risk factor. Age is the greatest risk factor for Alzheimer’s.
For most, symptoms first appear after age 65, though brain-imaging scans show that
the buildup of specific types of proteins related to Alzheimer’s can start wreckage long
before visible symptoms emerge.
Some of the genes linked to Alzheimer’s.
One is APOE, which has several forms. APOE e2 reduces your risk of Alzheimer’s,
while another, APOE e4, increases your risk. If you receive a copy of APOE e4 from
each of your parents, you’ll have the greatest odds of getting Alzheimer’s.
How you live matters.
Researchers have determined that nutritious food, exercise, sleep, socializing and other positive aspects of life are good preventive medicine for Alzheimer’s. One study showed that life changes can reduce your chance of developing Alzheimer’s by 35 percent.
Who you are matters.
Socioeconomic factors, including education, income and even where you live,
play a role in whether Alzheimer’s takes hold. Race matters, too: African Americans
are twice as likely to develop Alzheimer’s as Caucasians; Hispanics are 1.5 times more likely.
But we don’t know:
What causes the disease?
Scientists have yet to learn what triggers the early deposit of abnormal proteins in
the brain or how it damages brain neurons. It’s also unknown why a small percentage
of people who have plaque buildup don’t end up getting Alzheimer’s.
How these genes work.
Researchers have yet to figure out the complex genetic processes that are behind Alzheimer’s. Scientists only know the disease is likely the result of not just one gene
but of dozens of genes — and of the complex interactions that occur among them.
A medicine that works.
There are no drugs available to cure or slow down Alzheimer’s, though some may briefly help with its symptoms. Fully 99 percent of clinical trials of Alzheimer’s drugs fail, and some major pharmaceutical companies have stopped trying to develop this class of drugs.
What other factors might matter?
More study is needed to determine if social factors are causal or if they somehow help build up resilience to the disease through “cognitive reserve,” a sort of stockpile of brain strength, says Jennifer Manly at Columbia University in New York.
More on Brain Health:
Dementia vs. Alzheimer’s: Which is it?
Regular exercise boosts older adults’ brainpower
In search of the Alzheimer’s Answer aha! moment
What is dementia? Alzheimer’s Research UK
Depression | Alzheimer’s Association
Antidepressant and Alzheimer’s
Antidepressants called Selective Serotonin Reuptake Inhibitors (SSRIs)
are often used for people with Alzheimer’s and depression because they
have a lower risk than some other antidepressants of causing interactions
with other medications. See more
Dementia devastates the lives of everyone it touches, but our analysis
shows that women are bearing a disproportionate weight of the impact.
Our analysis shows that dementia became the leading cause of death for UK women
more than a decade ago, in 2011. Shockingly, it’s remained at this position ever since,
even at the height of the COVID-19 pandemic.
Two in three people with dementia (65%) are women, and longer life expectancy alone does not explain this disparity. Women are also more likely to care for a loved one with dementia – making up around two thirds of unpaid carers.
Yet across medical research, data from women is too often missing. And in the lab:
female dementia researchers are less likely to move into senior roles than men.
We’re calling for action to tackle dementia’s disproportionate impact on women.
And we must ensure women can make a full contribution to research, both as
participants and as researchers.
The government must deliver on its Dementia Moonshot promise to double research funding. And we’re urging them to convene a Dementia Medicines Taskforce to speed
up progress in finding new treatments for this devastating condition.
Alzheimer’s impact on women is disproportionate – Bing video
Alzheimer’s impact on women
By Staff Reports -May 5, 2023
To the Editor:
On May 14, millions of Americans will honor their mothers, grandmothers,
and great-grandmothers for their contributions to families and society.
Unfortunately, thousands in Ohio have already lost a mother or grandmother
to Alzheimer’s or are currently caring for someone living with the disease.
The hard truth is that Alzheimer’s disproportionately impacts women.
Two-thirds of all Alzheimer’s cases are in women, and an overwhelming
majority don’t know they are at an increased risk for the disease.
There is some good news regarding the inequality of Alzheimer’s occurrence in women. Scientists have identified a gene that appears to increase the risk of Alzheimer’s in women, providing a potential new clue as to why more women than men are diagnosed with the disease. Also, a new study shows that women can reduce their increased risk. Personalized lifestyle interventions — such as diet, exercise, stress reduction and sleep hygiene — were found to reduce Alzheimer’s risk factors in both sexes, but they worked even better in women.
In addition to learning more about why the genetics of being a woman increases the risk
of cognitive impairment, women can join clinical trials investigating the issues of women and Alzheimer’s risk. Women interested in finding out more about clinical trials can go
to alz.org/Trial Match a free matching tool for research studies and treatment trials for Alzheimer’s and other dementia. Anyone can participate. There are trials for those with and without the disease.
While lifestyles are proving to help reduce risks, not everything that makes up a woman’s lifestyle is by choice. Historically, women have fulfilled the role of caregiver for the family, and more than 60 percent of all caregivers are female.
They are our mothers, wives, aunts, sisters, and daughters. When caregiving is provided
to a loved one with Alzheimer’s or another dementia, the toll on the caregiver can be high.
According to the Alzheimer’s Association 2023.
Facts and Figures:
• More than 60 percent of Alzheimer’s and dementia caregivers are women,
and over one-third of them are daughters.
• The overwhelming majority of dementia caregivers who indicate a need for
individual counseling (85 percent) and respite care (84 percent) are women.
• Two and a half times as many women as men reported living with a person with dementia full time. Of those providing care to someone with dementia for more than
five years, 63 percent were women.
• Nearly 19% of female Alzheimer’s caregivers had to quit working either to become
full-time caregivers or because their caregiving duties became too burdensome.
There are 493,000 family and friends who provide unpaid care for loved ones living
with Alzheimer’s. These challenging and stressful caregiving responsibilities often fall
on female shoulders. Talk to your female relatives about women and Alzheimer’s risks
and learn the 10 warning signs.
You can call the 24/7 Helpline at 800-272-3900 for more information and assistance.
According to the History Channel, more phone calls are made on Mother’s Day than on any other day of the year. These holiday chats with Mom — often cause phone traffic to spike by as much as 37 percent. Ignore the increased phone traffic and call your mother this Mother’s Day – or any day for that matter.
Annemarie Barnett
Executive Director
Alzheimer’s Association Miami Valley and Greater Cincinnati Chapters
Source: Alzheimer’s impact on women is disproportionate – Bing video
The One Minute Cure : Madison Cavanaugh:
Free Download, Internet Archive
The One-Minute Cure reveals a remarkable, proven natural therapy that creates
an environment within the body where cancer cells, viruses, bacteria, and disease
microorganisms cannot thrive, thus enabling the body to CURE ITSELF of disease.
Over 91,000 research articles in the National Institutes of Health (USA) and
6,100 articles in European scientific literature have attested to the effectiveness
of this safe, powerful healing modality that costs only about 1-1/2 cents per day
to self-administer.
This 2nd Edition includes a new section showing how this one-minute protocol
makes the body uninhabitable by viruses― including the coronavirus―thereby
becoming “…the single most effective intervention for those battling COVID-19.”
The One – Minute Cure The Secret To Healing Virtually All Diseases – Bing video
Discover how this therapy has been administered by an estimated 15,000 European doctors, naturopaths and homeopaths to more than 10 million patients in the past 80 years to successfully treat practically every known disease, including cancer, AIDS, heart disease, diabetes, Alzheimer’s Disease, Parkinson’s Disease, hepatitis, multiple sclerosis, herpes, arthritis and asthma. The One-Minute Cure: The Secret to Healing Virtually All Diseases – 2nd Edition: Madison Cavanaugh: Amazon.com: Books
Stuart Varney: Biden is setting up the ‘greatest wealth transfer in history’
Border Patrol highlights more than 4,000 ‘gotaways’ following end of Title 42 (msn.com)
The myth of ‘greedflation’ is hiding the true culprits of rampant price rises (msn.com)
Full Video: Trump Spars With Nasty Kaitlan Town Hall Meeting 0n CNN (May 10, 2023)
CNN’s Trump Town Hall Spectacularly Backfires as Ratings Fall (msn.com)
The immigration Ponzi scheme is about to collapse (msn.com)
Vindicating Trump’s immigration policy.
As Democrats were falling over themselves calling Donald Trump an idiot after his
CNN town hall, the Biden White House was urgently working on something else: In fact, the White House that had resisted for years acknowledging it had created a crisis on the border was scrambling on Wednesday to publish a new regulation that looks suspiciously like the Trump policy it had fought to abolish. Example like Rush Limbaugh told Trump
in their interview that they’re jealous and want to make sure you don’t get the credit for solving the problem Interview with President Donald Trump on Rush Limbaugh | 10/9/20 – YouTube 0:00 / 2:27:03
Number of Migrant Crossings Drops After Lifting of Title 42.
(Probably Passing them through at 3AM―when Democrats do their best work.)
On May 14, the Biden administration said that migrant crossings at the U.S.-Mexico border have fallen since Title 42 expired. The numbers we have experienced in the past two days are markedly down over what they were prior to the end of Title 42, Alejandro Mayorkas, U.S. Homeland Security Secretary, via Reuters.
According to U.S. Homeland Security Secretary Alejandro Mayorkas, border patrol
agents have reported a 50% drop in crossings since May 11. Mayorkas said that criminal penalties for migrants entering the country illegally accounted for the decrease in illegal border crossings. There is a lawful, safe and orderly way to arrive in the United States.
That is through the pathways that President Biden has expanded in an unprecedented way, and then there’s a consequence if one does not use those lawful pathways,
Alejandro Mayorkas, U.S. Homeland Security Secretary, via Reuters.
Reuters reports that officials in communities near the border say that the expected
surge of migrants many fears will strain border facilities and towns is still on the way.
The number of migrants we were expecting initially – the big flow – is not here yet,
Victor Trevino, Mayor of Laredo, Texas, via Reuters.
Others pointed out that while the surge experienced at the border has yet to reach
the magnitude of what was expected, numbers still remain historically high. What the secretary failed to say is, this week has seen more crossings than any time, any week, in our history, Representative Mark Green, Republican chairman of the House Homeland Security Committee, via CNN The GOP proposal to raise the debt ceiling would force Americans on Social Security and Medicare to wait longer to receive help and make
college more expensive, the White House says (msn.com)
House Oversight GOP launches probe into FEMA over tax money
going to NGOs aiding illegal immigration (msn.com)
‘They Want A Default’: McCarthy Says House GOP Making Little Progress
With Biden On Debt Ceiling (msn.com)
‘Severe hardship to American families’ is inching closer and closer as Congress
fails to find a debt ceiling solution, Janet Yellen warns (msn.com)
DOJ ‘turning a blind eye’ as Biden corruption informant reportedly
goes missing, says GOP rep (msn.com)
Mayorkas warns surge of migrants at southern border post-
Title 42 is still possible: ‘Too early’ (msn.com)
Biden Administration Approves – Social Security, SSI, SSDI (Explained),
What happens to migrants processed at the southern border? | CUOMO – Bing video
66 hours: That’s about how long it takes for a migrant who first steps foot into the U.S.
to be processed, according to sources. NewsNation’s Robert Sherman joins Chris Cuomo
at the southern border to break down what exactly the process entails.
More: https://trib.al/t6svFh4 #migrants #southernborder #CUOMO
MAGA election deniers did worse in 2022 than other Republicans —
and Dems expect more ‘implosions’ in 2024 (msn.com)
Maddow Blog | GOP’s Comer ‘can’t track down’ his own anti-Biden ‘informant’ (msn.com)
Biden admin, NY officials slammed after homeless veterans booted from migrant hotels.
The big problem with trying to cut spending in a debt ceiling bill (msn.com)
LARRY KUDLOW: This is why conservatives are happier (msn.com)
Read More: What if Trump and Republicans were right on Title 42 and immigration?
Bill Melugin on Twitter: “NEW: Remarkable video from our Fox drone team shows an enormous line of hundreds of migrants who just crossed illegally into Brownsville, Texas.
A large majority of them are single adults. The RGV continues to see a massive surge of illegal crossings ahead of T42 drop. https://t.co/xHDV8sc8PD” / Twitter
* US Army soldier opens gate to let huge horde of migrants onto PRIVATE property
** US Army soldier opens gate to let huge horde of migrants onto PRIVATE property
Laughing Biden tells press post-Title 42 is ‘much better than you all expected’
US Army officer on active duty says squatter has moved into her Atlanta home