Nature is Grand

Pando is the scientific name of the largest organism on Earth – Bing video
 
What if we all embraced clean energy?
We imagined what a green US could look like in 2050. (msn.com)
A one-tree forest in Utah made up of 47,000 genetically identical trees, and millions of leaves, connected through one root system. That’s right, a single root system! It has been growing for close to 100,000 years. And yet another elegant display of the fractal nature
of her. I believe the collective human consciousness to be the same & interconnected in some way.

 Whereas the concept of bioenergy fields is thousands of years old.
Their existence has never been verified by scientific experiments designed
to detect and measure them; so bioenergy fields have no scientific credibility. 
The instruments used for those experiments typically detect components of the electromagnetic spectrum.
The experiments presented here utilize a detector that instead is sensitive to actual “pushing” forces that are capable of altering the momentum of a physical object such
as simple torsion pendulum balance that is suspended above a seated human subject. 

The experimental design includes a video camera connected to a computer that can detect and measure the pendulum movements with high precision, and store this information in a data file for later analysis. Experiments show that the pendulum detects and measures substantial forces that drastically alter the motions of the pendulum when a subject is seated under it. The following effects are consistently observed with every subject in every experiment performed up to now:

 1) Substantial shifts of the center of oscillation of the pendulum;
shifts as large as 2.2 cm (7 deg) requiring a force that is equivalent to 45 mg are observed,
 2) Many new frequencies of oscillation of the pendulum are introduced when a subject is present, 
 3) Dramatic changes in the amplitudes of oscillation of the pendulum are observed throughout the experiment; increasing, decreasing, and increasing again, in patterns
that resemble chemical relaxation processes, 
 4) These shifts of the center of oscillation, the new frequencies of oscillation, and the changes in amplitudes all persist for 30–60 min after the subject has left the pendulum.

This is inconsistent with the physics of a simple harmonic oscillator such as a torsion pendulum, which should return to simple harmonic oscillation immediately after any exterior disturbances are discontinued. After conducting control experiments to rule out effects of air currents and other artifacts, it is concluded that the effects are exerted by some kind of force field that is generated by the subject seated under the pendulum.

This is a Parts List that provides instructions for the construction of the pendulum
that was employed by Hansen and Lieberman. The Hansen and Lieberman articles are: Construction and Characterization of a Torsional Pendulum that Detects a Novel Form of Cranial Energy. And Use of a Torsion Pendulum Balance to Detect and Characterize What May Be a Human Bioenergy Field.  http://hdl.handle.net/1903/9421 http://hdl.handle.net/1903/15607

We know of no force, such as one within the electromagnetic spectrum that can account for these results. It may be that a conventional explanation for these surprising results will be discovered, but it is possible that we have observed a phenomenon that will require the development of new theoretical concepts. For now, it is important that other investigators repeat and extend our observations.

Browsing Chemistry & Biochemistry Research Works by Author “Hansen, J. Norman” 
Parts List for Pendulum of Hansen & Lieberman compiled by J. Norman Hansen nhansen@umd.edu 
Hansen, J. Norman (2014-10)
This is a Parts List that provides instructions for the construction of the pendulum that was employed by Hansen and Lieberman. The Hansen and Lieberman articles are:Construction and Characterization of a Torsional Pendulum …
A Reply to van den Berg and van der Sluys: Effects Resembling a Bio-Field on a Torsion Pendulum Cannot Be Caused by Heated Air Currents Generated by the Subject 
Hansen, J. Norman; Lieberman, Joshua A (Society of Scientific Exploration, 2015)

Treefall 
Hansen, John; Hansen, J. Norman; Hansen, John Norman (Vantage Press, 1999-12)
This file is an electronic facsimile of Treefall as published in book form by Vantage Press, 1999. It was authored by John Hansen, who is also J. Norman Hansen and John Norman Hansen at the University of Maryland, College …
Use of a Torsion Pendulum Balance to Detect and
Characterize What May Be a Human Bioenergy Field 
Hansen, J. Norman; Lieberman, Joshua A. (Society for Scientific Exploration, 2013-06)
Whereas the concept of bioenergy fields is thousands of years old, their existence has never been verified by scientific experiments designed to detect and measure them; so bioenergy fields have no scientific credibility. …

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Experiments have shown that human AURAs can swing a pendulum.

DISCOVERY
Humans Have a Mysterious Bioenergy Field
That Mystics Have Always Known About: Scientific Discovery
BY TARA MACISAAC
 For thousands of years, mystics have alluded to the presence of a biologically generated energy field, or aura, surrounding humans. Scientific investigation indicates this may be more than mere mysticism and folklore. Biochemist John Norman Hansen, Ph.D., at the University of Maryland has found evidence that such an energy field could be real,
lending credence to what spiritual practitioners have pointed to for eons. 
Dr. Hansen conducted hundreds of experiments with dozens of subjects, and his results are consistently replicable. Other scientists have also reproduced his results, including Willem H. van den Berg of the department of biochemistry and biophysics at the University of Pennsylvania, and physicist William van der Sluys at Gettysburg College, who published their study (pdf) in the Journal of Scientific Exploration on March 15, 2015. 

Previous investigation of human bioenergy fields has used photon sensors.
Dr. Hansen took a different approach. He wondered whether a bioenergy field, if it exists, would have enough force to push a torsion pendulum—a device sensitive enough to be moved by a subtle force. He hung the pendulum above the subject’s head and saw a clear change in the pendulum’s momentum. 
One of the outstanding observations was that the effect of the human presence continued for some 30 to 60 minutes after the human subject had already left. With other forces, such as air currents, the pendulum would immediately return to its classic, non-driven motion. 

The mental state of a subject can strongly affect the behavior of the pendulum. 
Every subject had roughly the same power to influence the pendulum “indicating that the effects on the pendulum require neither unique talent nor practice,” wrote Hansen in a synopsis of a talk he gave at the 34th annual Society for Scientific Exploration conference at the end of May 2015. “However, it has been observed that some subjects, especially ones that have pursued a meditative practice for many years, exert very different effects during a meditative state compared to a non-meditative state … which shows that the mental state of a subject can strongly affect the behavior of the pendulum.”  

Is There a Conventional Explanation? 
Van den Berg and van der Sluys used the same pendulum device—as Hansen had made the design public, encouraging others to replicate his results—and observed the same change in its movement when in proximity to a human head. They wondered, however, if this change may have been due to a change in air temperature from the heat emanated by a human head. The change in air temperature could cause convection currents, they said. 
They wondered, however, if this change may have been due to a change in air temperature from the heat emanated by a human head. 
They placed a layer of plastic between the head and the pendulum and found the effect on the pendulum disappeared. They suggested the plastic either cut the pendulum off from the mysterious bioenergy field, or it simply cut off the heat source. Hansen published a reply to this study, however, noting what he sees as flaws in the theory that body heat caused the pendulum movement. 

For starters, Hansen said, “If you were to place a thick plastic shield between the subject and the pendulum, the pushing force [of the bioenergy field] would initially be against the shield, and the pendulum would only respond to whatever pushing force remained after pushing against the shield. For the pushing force to survive passage through the shield and then push against the pendulum would violate fundamental principles of physics; i.e. you can only use a force once, and if it is utilized to push against the shield it cannot subsequently push against the pendulum.” 
Another factor Hansen said that van den Berg failed to take into account is the persistent aftereffects. Hansen wrote: “A fundamental principle of pendulum physics is that if the pendulum is driven by an outside force and the force is removed, then the pendulum will immediately return to classic non-driven motion.” 

Any accumulation of heated convection currents would quickly dissipate after the subject left. So convection currents could not explain these aftereffects. Hansen described the effects of the subject’s bioenergy field as being somehow “imprinted” on the pendulum.
He said the van den Berg study also failed to acknowledge the varied frequencies with which the pendulum oscillates in the presence of a human subject. The pendulum oscillates with a single frequency when the subject is absent. It oscillates with many new frequencies when the subject is present, and for some half an hour or more after the subject has left—something not explained away by convection currents caused by air temperature variations. 
 
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How does cancer outsmart your immune system? 
Here are a few theories:

How Cancer Fools the Immune System
How to Activate Your Immune System to Fight Against Cancer – Search (bing.com)
Your immune system attacks “foreign invaders” — cells or organisms it does not recognize. Cancer cells start out as normal cells. If the changes (mutations) in the cell do not make it seem “foreign” to the immune system, the cancer cells can grow and multiply without being attacked.
Cancer cells can turn off your body’s natural immune response and suppress the activity
of local immune cells (which protect a specific organ or other part of the body). Within a tumor, the cancer cells can create an environment that interferes with the effectiveness of the immune response.

Immunoediting is the theory that, as far as the immune system goes,
there are three stages of tumor growth:

Expansion: The tumor grows and eventually comes to the attention of the immune system. Under normal circumstances, cell growth and reproduction are controlled activities.
But as the cells mutate into cancer cells, the control switch gets turned off, and cell growth and reproduction explode. Eventually the abnormal cells will begin to produce abnormal antigens. The immune system detects these abnormal antigens and attacks the cancer cells.

Equilibrium: Now the cancer cells and the immune system battle it out.
The tumor may be destroyed or just go dormant (not growing, inactive).

Escape: While dormant, the tumor undergoes more mutations.
In an effort to escape destruction, the cancer cells stop making the abnormal antigens.
If they succeed, then they can grow again — this time undetected by the immune system.
In these circumstances, there is nothing “wrong” with the immune system; it is just unaware of the problem. It’s like fire trucks sitting in the station, gassed up and ready to go — but an alarm must go off before they can go to the scene and work to put out the fire.

Helpful ways to strengthen your immune system and fight off disease
How can you improve your immune system? On the whole, your immune system
does a remarkable job of defending you against disease-causing microorganisms.
But sometimes it fails: A germ invades successfully and makes you sick.
Make other lifestyle changes in the hope of producing a near-perfect immune response?
What if you improve your diet? Take certain vitamins or herbal preparations?
Is it possible to intervene in this process and boost your immune system?

What can you do to boost your immune system?
The idea of boosting your immunity is enticing, but the ability to do so has proved elusive for several reasons. The immune system is precisely that — a system, not a single entity.
To function well, it requires balance and harmony. There is still much that researchers don’t know about the intricacies and interconnectedness of the immune response.
For now, there are no scientifically proven direct links between lifestyle and enhanced immune function.
But that doesn’t mean the effects of lifestyle on the immune system aren’t intriguing
and shouldn’t be studied. Researchers are exploring the effects of diet, exercise, age, psychological stress, and other factors on the immune response, both in animals and in humans. In the meantime, general healthy-living strategies make sense since they likely help immune function and they come with other proven health benefits.

Immunity in action
Photos courtesy of Michael N. Starnbach, Ph.D.,
Harvard Medical School

Immunity in action. 
A healthy immune system can defeat invading pathogens as shown above,
where two bacteria that cause gonorrhea are no match for the large phagocyte,
called a neutrophil, that engulfs and kills them (see arrows).

Healthy ways to strengthen your immune system:
Your first line of defense is to choose a healthy lifestyle.
Following general good-health guidelines is the single best step you can take toward naturally keeping your immune system working properly. Every part of your body, including your immune system, functions better when protected from environmental assaults and bolstered by healthy-living strategies such as: Don’t smoke.

What smoking does to your body,
Nicotine shrinks your arteries,
Eat a diet high in fruits and vegetables.
Exercise regularly.
Maintain a healthy weight.
Try to minimize stress.
If you drink alcohol, drink only in moderation.
Get adequate sleep.
Take steps to avoid infection, such as washing
your hands frequently and cooking meats thoroughly.
10 Natural Ways to Increase Your Glutathione Levels (healthline.com)

Increase immunity the healthy way Selenium and Glutathione.
Many products on store shelves claim to boost or support immunity.
But the concept of boosting immunity actually makes little sense scientifically.
In fact, boosting the number of cells in your body — immune cells or others —
is not necessarily a good thing.
For example, athletes who engage in “blood doping” — pumping blood into their systems to boost their number of blood cells and enhance their performance — run the risk of strokes.
Attempting to boost the cells of your immune system is especially complicated because there are so many different kinds of cells in the immune system that respond to so many different microbes in so many ways. Which cells should you boost, and to what number?
So far, scientists do not know the answer. What is known is that the body is continually generating immune cells. Certainly, it produces many more lymphocytes than it can possibly use. The extra cells remove themselves through a natural process of cell death called apoptosis — some before they see any action, some after the battle is won.
No one knows how many cells or what the best mix of cells the immune system needs to function at its optimum level.

Immune system and age
As we age, our immune response capability becomes reduced, which in turn contributes to more infections and more cancer. As life expectancy in developed countries has increased, so too has the incidence of age-related conditions.
While some people age healthily, the conclusion of many studies is that, compared with younger people, the elderly are more likely to contract infectious diseases and, even more importantly, more likely to die from them. Respiratory infections, including, influenza, the COVID-19 virus and particularly pneumonia are a leading cause of death in people over 65 worldwide. No one knows for sure why this happens, but some scientists observe that this increased risk correlates with a decrease in T cells, possibly from the thymus atrophying with age and producing fewer T cells to fight off infection. Whether this decrease in thymus function explains the drop in T cells or whether other changes play a role is not fully understood. Others are interested in whether the bone marrow becomes less efficient at producing the stem cells that give rise to the cells of the immune system.

A reduction in immune response to infections has been demonstrated by older people’s response to vaccines. For example, studies of influenza vaccines have shown that for people over age 65, the vaccine is less effective compared to healthy children (over age 2). But despite the reduction in efficacy, vaccinations for influenza and S. pneumoniae have significantly lowered the rates of sickness and death in older people when compared with no vaccination.
There appears to be a connection between nutrition and immunity in the elderly. A form of malnutrition that is surprisingly common even in affluent countries is known as “micronutrient malnutrition.” Micronutrient malnutrition, in which a person is deficient in some essential vitamins and trace minerals that are obtained from or supplemented by diet, can happen in the elderly. Older people tend to eat less and often have less variety in their diets. One important question is whether dietary supplements may help older people maintain a healthier immune system. Older people should discuss this question with their doctor.

Diet and your immune system
Like any fighting force, the immune system army marches on its stomach. Healthy immune system warriors need good, regular nourishment. Scientists have long recognized that people who live in poverty and are malnourished are more vulnerable to infectious diseases. For example, researchers don’t know whether any particular dietary factors, such as processed foods or high simple sugar intake, will have adversely affect immune function. There are still relatively few studies of the effects of nutrition on the immune system of humans.
There is some evidence that various micronutrient deficiencies — for example, deficiencies of zinc, selenium, iron, copper, folic acid, and vitamins A, B6, C, and E — alter immune responses in animals, as measured in the test tube. However, the impact of these immune system changes on the health of animals is less clear, and the effect of similar deficiencies on the human immune response has yet to be assessed.

So, what can you do?
If you suspect your diet is not providing you with all your micronutrient needs — maybe, for instance, you don’t like vegetables — taking a daily multivitamin and mineral supplement may bring other health benefits, beyond any possibly beneficial effects on the immune system. Taking megadoses of a single vitamin does not. More is not necessarily better.

Improve immunity with herbs and supplements?
Walk into a store, and you will find bottles of pills and herbal preparations that claim to “support immunity” or otherwise boost the health of your immune system. Although some preparations have been found to alter some components of immune function, thus far there is no evidence that they actually bolster immunity to the point where you are better protected against infection and disease. Demonstrating whether an herb — or any substance, for that matter — can enhance immunity is, as yet, a highly complicated matter. Scientists don’t know, for example, whether an herb that seems to raise the levels of antibodies in the blood is actually doing anything beneficial for overall immunity.

Stress and immune function
Modern medicine has come to appreciate the closely linked relationship of mind and body. A wide variety of maladies, including stomach upset, hives, and even heart disease, are linked to the effects of emotional stress. Despite the challenges, scientists are actively studying the relationship between stress and immune function.
For one thing, stress is difficult to define. What may appear to be a stressful situation for one person is not for another. When people are exposed to situations they regard as stressful, it is difficult for them to measure how much stress they feel, and difficult for the scientist to know if a person’s subjective impression of the amount of stress is accurate. The scientist can only measure things that may reflect stress, such as the number of times the heart beats each minute, but such measures also may reflect other factors.

Most scientists studying the relationship of stress and immune function, however, do not study a sudden, short-lived stressor; rather, they try to study more constant and frequent stressors known as chronic stress, such as that caused by relationships with family, friends, and co-workers, or sustained challenges to perform well at one’s work. Some scientists are investigating whether ongoing stress takes a toll on the immune system.
But it is hard to perform what scientists call “controlled experiments” in human beings.
In a controlled experiment, the scientist can change one and only one factor, such as the amount of a particular chemical, and then measure the effect of that change on some other measurable phenomenon, such as the amount of antibodies produced by a particular type of immune system cell when it is exposed to the chemical.
In a living animal, and especially in a human being, that kind of control is just not possible, since there are so many other things happening to the animal or person at the time that measurements are being taken. Despite these inevitable difficulties in measuring the relationship of stress to immunity, scientists are making progress.

Does being cold give you a weak immune system?
Almost every mother has said: “Wear a jacket or you’ll catch a cold!” Is she right? Probably not, exposure to moderate cold temperatures doesn’t increase your susceptibility to infection. There are two reasons why winter is “cold and flu season.” In the winter, people spend more time indoors, in closer contact with other people who can pass on their germs. Also the influenza virus stays airborne longer when air is cold and less humid.
But researchers remain interested in this question in different populations. Some experiments with mice suggest that cold exposure might reduce the ability to cope with infection.

But what about humans?
Scientists have performed experiments in which volunteers were briefly dunked in cold water or spent short periods of time naked in subfreezing temperatures.  They’ve studied people who lived in Antarctica and those on expeditions in the Canadian Rockies. The results have been mixed. For example, researchers documented an increase in upper respiratory infections in competitive cross-country skiers who exercise vigorously in the cold, but whether these infections are due to the cold or other factors — such as the intense exercise or the dryness of the air — is not known.
A group of Canadian researchers that has reviewed hundreds of medical studies on the subject and conducted some of its own research concludes that there’s no need to worry about moderate cold exposure — it has no detrimental effect on the human immune system.

Should you bundle up when it’s cold outside?
The answer is “yes” if you’re uncomfortable, or if you’re going to be outdoors for an extended period where such problems as frostbite and hypothermia are a risk. But don’t worry about immunity.

Exercise: Good or bad for immunity?
Regular exercise is one of the pillars of healthy living. It improves cardiovascular health, lowers blood pressure, helps control body weight, and protects against a variety of diseases. But does it help to boost your immune system naturally and keep it healthy? Just like a healthy diet, exercise can contribute to general good health and therefore to a healthy immune system. 

Unbelievable: Cells Eat and Drink- But What Does It Have to Do With Defense? #cell #biology #dna – YouTube

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Biochemistry and Molecular Biology Education

Book ReviewFree Access
Biochemistry

Jeffrey C. HansenNorman P. Curthoys
First published: 04 February 2013
 https://doi.org/10.1002/bmb.20656 
 Christopher K. Mathews, Kensal E. Holde, Dean R. Appling, Spencer J. Anthony-Cahill, Pearson Canada, Toronto, 2012, 1342 pages, ISBN 978-0-13-800464-4 (Hardcover $201.40), also available as an e-book.
This new edition of a popular textbook is an excellent choice for students who require a comprehensive treatment of molecular and cellular biochemistry. We teach a two semester biochemistry course taken predominantly by junior and senior biochemistry majors. The first semester covers macromolecular structure while the second semester covers metabolism. A complete text is needed for such a course, but there are many fine books to choose from and the competition is fierce. We have used the earlier editions of Biochemistry and were curious to see how the 4th edition has been improved. 

The most obvious change is the addition of two new co-authors, Dean Appling (University of Texas at Austin) and Spencer Anthony-Cahill (Western Washington University). The writing strengths of Mathews and van Holde (Oregon State University) have been aptly demonstrated in the three previous editions. The addition of Appling and Anthony-Cahill has improved many areas of the book, such as protein structure, enzyme kinetics, and one-carbon metabolism.
The 3rd edition of Biochemistry was published in 2000, and like the first two editions,
was very well received. However, a 12-year layoff is an eternity for a popular textbook.
The challenge facing the authors was to update the text without changing the things
that made it attractive in the first place. The three chapters that make up Section 1
(The Realm of Biochemistry) are largely unaltered and
provides an insightful introduction to biochemical fundamentals. 
We particularly appreciated the discussion of non-covalent interactions in Chapter 2
and biochemical energetics in Chapter 3. Although van Holde has a reduced role in the
4th edition, his contributions remain a strength. 
The seven chapters that make up Section 2 (The Molecular Architecture of Living Matter)
provide an informative treatment of the structure and function of nucleic acids, proteins,
carbohydrates and lipids. Chapter 4 (Nucleic Acids) could be significantly improved. 

The presentation of the classic Meselson and Stahl experiment early in this chapter is rather ineffective and cumbersome since DNA replication has yet to be discussed, while the brief introductions to transcription, replication, and translation that appear later seem out of place in a chapter dedicated primarily to the structure and properties of nucleic acids. We also would have liked a state-of-the-art discussion of RNA folding and tertiary structures. The chapters on protein structure are satisfying, although the authors missed the opportunity to include a cogent discussion of how disordered proteins defy the classical protein folding paradigm. 

Chapter 7 is entitled “Protein Function and Evolution,” but this is somewhat misleading since this chapter really is a detailed discussion of the structure and function of the globulins and immunoglobulins. That being said, the choice of these proteins is appropriate for illustrative purposes. We liked Chapter 8 and its thorough biochemical treatment of contractile proteins and molecular motors, although some of our students struggled with the complexity of this material.
Section 3 (Dynamics of Life: Catalysis and Control of Biochemical Reactions) consists of two chapters. Chapter 11 (Enzymes) has been extensively re-worked and presents a fresh view of enzyme kinetics and reaction mechanisms, reflecting Appling’s expertise in these areas. Chapter 11 (Chemical Logic of Metabolism) is a straightforward introduction to the chemistry of metabolism. It is not clear why these two chapters are grouped together into a separate section. Chapter 11 could just as easily have been placed in Section 2 and Chapter 12 in Section 4.
Section 4 (Dynamics of Life: Energy, Biosynthesis, and Utilization of Precursors) is devoted to the discussion of metabolism.
This section contains 11 chapters (13 through 23) and is organized using the classical separation of carbohydrates, citric acid cycle, bioenergetics, lipids, nitrogenous compounds, and nucleotides. Collectively, these chapters provide a clear, concise, and easy to follow coverage of the individual pathways involved in metabolism. 
The discussion covers the chemistry of metabolic reactions with sufficient detail that students should gain an appreciation of the chemical properties of key metabolites and the logic and energetics of anabolic and catabolic pathways. 

The presentation of metabolic regulation is current and clearly explained. We did find, however, that many of the illustrations in these chapters are overly simplistic and more detailed figures could be incorporated to add clarity to the complex concepts and regulatory mechanisms that are discussed in the text. 
The material on metabolic regulation is interjected throughout the various chapters but a focused discussion of how regulation integrates with the physiological function of various organs is missing. 
The authors also frequently mix discussion of metabolism that is unique to mammals, prokaryotes, or plants, which will lead to some confusion among students. Membrane transport and the energetics and distinguishing properties of various transport systems are briefly discussed earlier in the book in the chapter on lipids. 
However, the importance of transport in the various aspects of mammalian metabolism could be better emphasized throughout Section 4. For example, it is our experience that a discussion of how the intestine carries out the absorption and transepithelial transport of glucose and how the properties of different glucose transporters influence how various tissues extract and metabolize glucose can be of more interest to students than focusing on the details of the individual reactions of the glycolytic pathway.

 Chapter 18 briefly covers important current topics in interogran relationships, including the roles of AMP-kinase, mTOR signaling, protein acetylation, and sirtuins in the regulation of metabolism. However, it is unclear why this chapter precedes the discussion of amino acid metabolism. As it stands, the amino acid chapter details the pathways of their synthesis and degradation without highlighting the interorgan nature and overall importance of amino acid catabolism. 
The treatment of starvation and diabetes also is cursory; a more detailed and up-to-date presentation of these topics is an excellent way to integrate and summarize nearly all of the material covered in a course on metabolism. Finally, the discussion of insulin and glucagon signaling in Chapter 23 (Mechanisms of Signal Transduction) could easily be expanded given the importance of the two hormones in the overall integration and regulation of metabolism. While it is typical of textbooks to describe signal transduction and interorgan relationships separately, we find that these two topics are more effectively taught if they are integrated into the various chapters on metabolic pathways and their regulation.

Section 5 (Information) has been expanded and now consists of six chapters that cover what the authors refer to as genomic biochemistry. The chapters in this section focus on the macromolecules involved in DNA replication (Chapter 25), DNA restructuring (Chapter 26), prokaryotic and eukaryotic transcription (Chapter 27), and translation (Chapter 28), which gives a biochemical tilt to material often covered in a molecular biology class. The one exception is Chapter 24, (Genes, Genomes, and Chromosomes),
a new chapter that is more of a brief primer on molecular genetics.
Also new to the 4th edition is Chapter 29 (Regulation of Gene Expression),
which covers transcriptional regulation in prokaryotes and eukaryotes,
epigenetics, regulation of translation, and RNA interference.
A continuing strength is the ‘Tools of Biochemistry” series that closes many
of the chapters. X-ray crystallography and NMR, proteomics and metabolomics,
and the polymerase chain reaction are just a few of the 28 relevant biochemical techniques/protocols that are nicely explained. Too often the experimental side of biochemistry is missing from popular textbooks, but that is not the case here.

To gain a student’s perspective we enlisted the opinions of several undergraduates currently enrolled in our course (J. Haskins, C. Hendrich, Y. Lu, M. Staros, K. Thompson, E. Webster, P. Zhuang). As a whole, the text was very well received. The students generally found the material to be interesting and the writing clear and concise. Difficult topics such as hemoglobin allosterism were more problematic but that is to be expected. Notable specific comments from our students included, “this chapter is well organized and the information accessible to the reader,” “I wish all my textbooks were this clear and easy to read,” and “I learned a lot.”
Altogether, the 4th edition of Biochemistry has not lost its earlier appeal. Most of our criticisms have to do with presentation rather than content, which is to say that they are minor. The text may be too detailed for a typical single semester biochemistry class, but is well suited for a more sophisticated two semester course. Both instructors and students alike should find the 4th edition to be a worthy addition to the long list of comprehensive biochemistry textbooks.

Jeffrey C. Hansen
Norman P. Curthoys
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, 80523

Macromolecular Biochemistry
Macromolecular Biochemistry is the study of large, polymeric, biological molecules including carbohydrates, lipids, nucleic acids, and proteins. Faculty in BE are studying many aspects of this field including developing novel methods to deliver macromolecular pharmaceuticals and producing technologies to study the role of polysaccharides in disease processes.
Pages
Eric Alm, PhD
Michael Birnbaum, PhD
Paul Blainey, PhD
Peter Dedon, MD, PhD
John M. Essigmann, PhD
Alan J. Grodzinsky, ScD
Anders Sejr Hansen, PhD
Alan Jasanoff, PhD
Amy E. Keating, PhD
Alexander M. Klibanov, PhD
Harvey F. Lodish, PhD
Jacquin C. Niles, MD, PhD
Leona D. Samson, PhD
Ram Sasisekharan, PhD
Peter So, PhD
Steven R. Tannenbaum, PhD
Bruce Tidor, PhD
Christopher A. Voigt, PhD
K. Dane Wittrup, PhD
Dr Peter Dingle

Sodium Bicarbonate (baking soda) – Understanding his POWER – Dr. Sircus
Getting More of This Mineral Could Stave Off Dementia, New Study Finds (msn.com)
A Torsional Pendulum that Detects Bioenergy | J. Norman Hansen – YouTube
Big Pharma and the Chinese Communist Party | Brian T. Kennedy – YouTube
Biochemistry Jeffrey C. Hansen, Norman P. Curthoys – Search (bing.com)
Glutamine metabolism: Role in acid-base balance* – PubMed (nih.gov)
Lemon, Apple Cider Vinegar or Sodium Bicarbonate Facebook
Potassium Sodium and Alzheimer’s – Search (bing.com)
Baking Soda & cancer By Vernon Johnson – Bing video
Write your own story – Sidney Daily News

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