Chronic Inflammation = Cancer Metastases

Metastases is the plural form of metastasis. Cancer.net – Search (bing.com)

Having Self Belief in his own research saved his life!!!
James McCraw was diagnosed with Stage IV Glioblastoma Multiforme, an aggressive brain cancer, after experiencing seizures 1. He underwent surgery, chemotherapy, and radiation, but only ½ of the tumor was removed, and he was given a prognosis of only 14 months to live 1. The tumor returned in December 2015, and James’s oncologist was thinking about
a new surgery and chemotherapy but decided to consult a specialist who decided to wait another three months before making a new resonance 2.  

Placebo Effect: Meaning, Examples, and Impact (verywellmind.com)
Your mind can be a powerful healing tool when given the chance. The idea that your brain can convince your body a fake treatment is the real thing — the so-called placebo effect — and thus stimulate healing has been around for millennia. Now science has found that under the right circumstances, a placebo can be just as effective as traditional treatments.
“The placebo effect is more than positive thinking — believing a treatment or procedure will work. It’s about creating a stronger connection between the brain and body and how they work together,” says Professor Ted Kaptchuk of Harvard-affiliated Beth Israel Deaconess Medical Center, whose research focuses on the placebo effect.
Placebos won’t lower your cholesterol or shrink a tumor. Instead, placebos work on symptoms modulated by the brain, like the perception of pain. “Placebos may make you feel better, but they will not cure you,” says Kaptchuk. “They have been shown to be most effective for conditions like pain management, stress-related insomnia, and cancer treatment side effects like fatigue and nausea.”

Does the placebo effect mean failure or success?
For years, a placebo effect was considered a sign of failure. A placebo is used in clinical trials to test the effectiveness of treatments and is most often used in drug studies. For instance, people in one group get the actual drug, while the others receive an inactive drug, or placebo. The participants in the clinical trial don’t know if they receive the real thing or the placebo.
This way, the researchers can measure if the drug works by comparing how both groups react. If they both have the same reaction — improvement or not — the drug is deemed not to work. More recently, however, experts have concluded that reacting to a placebo is not proof that a certain treatment doesn’t work, but rather that another, non-pharmacological mechanism may be present.

How placebos work is still not quite understood, but it involves a complex neurobiological reaction that includes everything from increases in feel-good neurotransmitters, like endorphins and dopamine, to greater activity in certain brain regions linked to moods, emotional reactions, and self-awareness. All of it can have therapeutic benefits.
“The placebo effect is a way for your brain to tell the body what it needs to feel better,”
says Kaptchuk.

But placebos are not all about releasing brainpower. You also need the ritual of treatment. “When you look at these studies that compare drugs with placebos, there is the entire environmental and ritual factor at work,” says Kaptchuk. “You have to go to a clinic at certain times and be examined by medical professionals in white coats. You receive all kinds of exotic pills and undergo strange procedures. All this can have a profound impact on how the body perceives symptoms because you feel you are getting attention and care.”

Metastases most commonly develop when cancer cells break away from the main tumor and enter the body’s bloodstream or lymphatic system. These systems carry fluids around the body. 

Chemotherapy and radiation will reduce the tumor, but it will definitely cause it to metastasize. It may not be immediately, but it will make it metastasize with a vengeance eventually. Role of inflammation in cancer initiation – Search (bing.com)

Inflammation and Cancer: Triggers, Mechanisms, and Consequences – PubMed (nih.gov)

Anti-Inflammatory Agents for Cancer Therapy – PubMed (nih.gov)

Inflammation and cancer – PubMed (nih.gov)

At this point it may be too late
A small part of the tumor that is called the Cancer Stem Cells. The Cancer Stem Cells
are resistant to chemotherapy and radiation. You can do what you want but it is going to metastasize. There are a number of ways to kill the Cancer Stem Cells.

The most common way is to eat an anti-inflammatory diet.
I cook with only avocado oil and extra virgin olive oil,
Keep sugar to a minimum, no fast foods.

Inflammation to be Avoided.
Red Meat & Processed Meat
Also, Feedlot-Raised Meat
Artificial Food Additives
Dairy Products
Refined Grains
Alcohol
Glucose
Sugar

Cancer stem cells as key drivers of tumour progression
Challengingly, conventional cancer treatments target the bulk of the tumor and are unable to target CSCs due to their highly resistance nature, leading to metastasis and tumor recurrence.

Conclusion
Given dynamic cellular events along the cancer progression and contributions of resistance nature by CSCs, understanding their molecular and cellular regulatory mechanism in a heterogeneous nature, provides a significant cornerstone for the development of CSC-specific therapeutics.

Cancer stem cells drive tumor progression – Search (bing.com)
Central to all cancers is inflammation and that the cell processes involved in inflammation not only are responsible for initiation of the cancer, but also persist during its growth and play a central role throughout every phase of the cancer’s existence, including progression, invasion, angiogenesis, and metastasis.
 
21 Foods That Can Save Your Heart (webmd.com)

Turmeric/Curcumin – I use 1-2 tablespoons of Turmeric. Turmeric/Curcumin will cross the Brain Barrier (BBB) . I was confused. From the number of people asking me I think I should try and clear it up now. Turmeric does not fight cancer. A part of turmeric called curcumin is the cancer fighter. There is only 3%-5% of curcumin in turmeric. I do not take capsules, I prefer Turmeric powder. Because I am indolent, I take 1-2 teaspoons of turmeric and a touch of black pepper is great for preventive measures or maintenance.

• If you have cancer, you need 8g-12g (8g = 3-2/3 teaspoons) of curcumin daily for 3 months
(that is all they tested it for and could not a problem: see GRAS in a later chapter) and a touch of black pepper to get it past the liver.

You cannot get there by taking Turmeric.
It does not matter whether you are using turmeric powder, Turmeric Capsules, Golden Paste or any other form. If you are fighting cancer the best way to do this is by taking curcumin power. If you are not fighting cancer, then you need much less. Then you can
use turmeric in capsules, Golden Paste, or whatever you use Turmeric in.

image.png
 Curcumin can stain your countertop.

Amazon.com: Smarter Nutrition Curcumin Softgels – Potent & Bioavailable, 
This is the Curcumin I am now taking. It has Curcumin, Black Seed Oil and Ginger.
Conversion for Curcumin – 8-12 grams of Curcumin if you are battling cancer. 8 grams = 16 capsules = about 4 teaspoons (Curcumin is 3-5% of Turmeric) it is the cancer fighter. You cannot do enough Turmeric to fight cancer.

James McCraw  replied to Lucy Pestana‘s comment: 
 “Lucy Pestana I am not to tell you what to do. You have to make that choice. I am telling you that I believe that chemotherapy leads to metastasis based on my research and a lot of doctors research. https://pubmed.ncbi.nlm.nih.gov/25025713/ Abstract Since the first prospective identification of cancer stem cells in solid cancers the cancer stem cell hypothesis has reemerged as a research topic of increasing interest.

It postulates that solid cancers are organized hierarchically with a small number of cancer stem cells driving tumor growth, repopulation after injury and metastasis. They give rise to differentiated progeny, which lack these features. The model predicts that for any therapy to provide cure, all cancer stem cells have to be eliminated while the survival of differentiated progeny is less critical. In this review we discuss recent reports challenging the idea of a unidirectional differentiation of cancer cells.

These reports provide evidence supporting the idea that non-stem cancer cells exhibit
a remarkable degree of plasticity that allows them to re-acquire cancer stem cell traits, especially in the context of radiation therapy. We summarize conditions under which differentiation is reversed and discuss the current knowledge of the underlying mechanisms. https://pubmed.ncbi.nlm.nih.gov/18030004/ 

Abstract Recently it is considered that there is a small population of cells with stem cell property not only in leukemia but also in solid cancer. These cells show the ability of self-renewal and multi-potential differentiation, and can initiate and maintain a tumor. The origin of cancer stem cells might be their normal stem cells, progenitor cells, or bone marrow-derived cells. It is still difficult to isolate cancer stem cells in solid cancer.

There are three possible methodologies to isolate or identify cancer stem cells; the use
of a surface marker, use of cells cultured in a specific condition (sphere), or the use of side population cells identified by FACS. The gold standard assay that fulfills the definition of cancer stem cell may be serial transplantation in animal models. Cancer stem cells are likely to be responsible for disease relapse or metastasis, and also for resistance to radiation or conventional chemotherapy.

The stem cell niche plays an important role in maintaining cancer stem cells. The novel promising therapies against cancer stem cells are considered, including antibody-based therapy, signal inhibitors, overcoming radiation and drug resistance, or differentiation therapy. Another interesting therapy targeting the niche may also be considered.

PubMed Disclaimer Cancer stem cells – PubMed (nih.gov) Abstract Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities of self-renewal, differentiation, and tumorigenicity when transplanted into an animal host. A number of cell surface markers such as CD44, CD24, and CD133 are often used to identify and enrich CSCs. A regulatory network consisting of microRNAs and Wnt/β-catenin, Notch, and Hedgehog signaling pathways controls CSC properties.

The clinical relevance of CSCs has been strengthened by emerging evidence, demonstrating that CSCs are resistant to conventional chemotherapy and radiation treatment and that CSCs are very likely to be the origin of cancer metastasis. CSCs are believed to be an important target for novel anti-cancer drug discovery. Herein we summarize the current understanding of CSCs, with a focus on the role of miRNA and epithelial-mesenchymal transition (EMT), and discuss the clinical application of targeting CSCs for cancer treatment. Copyright © 2012 Elsevier Ltd. All rights reserved.

PubMed Disclaimer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651409/?fbclid=IwAR3Stpn_6VvBIcmiFDOpvF7o_SOZAA07dREsSDmaWUYPpvUofQzlw8Glkw 
Abstract Background Nowadays, we believe that cancer is a genetic disease. 

We focus on the genetic targets and epigenetic changes in a tumor. Remarkably, many crucial signal pathways in a malignant cell involve “stem-ness” genes. The prevalence of stem-ness in cancer suggests that cancer has a stem-cell origin and is a stem-cell disease. Presentation of the hypothesis The observation that many innate stem-ness properties are easily interchangeable with malignant hallmarks needs to be further elucidated.

There appears to be a malignant potential in every stem cell and a stem cell potential in every malignant cell. I hypothesize that cancer is a stem-cell disease rather than a genetic disease. Testing the hypothesis We will use homeobox genes to endow a certain progenitor cell with specific stem-ness properties and confer different stem-cell phenotypes to the particular cell type in a hierarchical manner.

We will demonstrate that an earlier homeobox gene plus a genetic defect (such as Pten loss) tend to form a more virulent tumor, while a later homeobox gene plus the same genetic defect tend to express a more indolent phenotype.
More Importantly, we will show that in clinically relevant cancer subtypes, those with worse clinical outcomes may paradoxically harbor fewer genetic mutations than those with better outcomes do.

Implications of the hypothesis The recognition that cancer is a stem-cell disease will instigate major paradigm shifts in our basic understanding of cancer. Many fundamental principles of oncology, such as multistep carcinogenesis, need to be reconciled. The realization that cancer is a stem-cell disease will also have profound clinical implications on personalized care. Many aspects of our current clinical trials need to be reevaluated.”

A Radical & Controversial Approach To STARVING CANCER:
The Two Root Causes | Dr. Thomas Seyfried (youtube.com)

Cancer Stem Cells (CSCs) have recently been identified in several solid tumors,
including Brain, Breast, Colon, Head and Neck, Liver, Lung, Ovary, Pancreas, Prostate,
Melanoma, Multiple Myeloma, Non-melanoma skin cancer, Stomach.

The only way to be cancer free is by killing the Cancer Stem Cells.
The tumor has a small part that is called the Cancer Stem Cells (usually 1% – 5%), It is the target. Most Oncologists focus on the tumor. That is what they are taught by Big Pharma. It is not the Oncologist fault, they believe it. Oncologists think they are doing right because the chemotherapy and radiation shrinks the tumor. Chemotherapy and radiation causes the cancer to metastasize.
Do not worry about the tumor, the tumor is there to save your life. It is a container to keep the harmful stuff in. It is like Pandora’s Box. The tumor is not the problem. It is the Cancer Stem Cells that are the problem. Cancer Stem Cells are a small part of the tumor. Cancer Stem Cells are resistant to chemotherapy and radiation. If you do the traditional cancer therapy (SOC), chemotherapy and radiation your cancer is coming back. It might not be immediately, but it will come back with a vengeance. 

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Researchers Reveal How Garlic Kills Brain Cancer Cells (powerofpositivity.com)

Balance of Nature Pills (Read Before Buying this Supplement) (lifehackerguy.com)

Local garlic will kill the Cancer Stem Cells if it is done properly. 
You must take a clove of local garlic, chop it up or grind it,
let it sit for 15 minutes before consuming it. 

Do not cook the garlic.
I was driving for Uber and didn’t want to smell like garlic.
I forgot the methods of taking garlic. The cancer came back. I refused to resume chemotherapy even though the Oncologist said I might die. The cancer went into remission. This was in 2014. I haven’t done chemotherapy since 2014.
My MRI’s are now scheduled for every 3 years  ~James McCraw

Anti-Inflammatory Lifestyle for Prevention and Treatment of Cancer by Bharat B. Aggarwal, PhD (youtube.com) 

He didn’t establish a cure; he discovered an unusual metabolic feature of cancer. where cancer cells preferentially perform anaerobic metabolism and secrete lactic acid, cancer treatments such as surgery, chemotherapy, radiation, immunotherapy, and targeted therapy do work the contributions of cancer cell metabolism to metastasis | Disease Models & Mechanisms | The Company of Biologists

Anti-Inflammatory Lifestyle for Prevention and Treatment of Cancer by Bharat B. Aggarwal, PhD (youtube.com)
Brilliant video where is the other part to the video talking about curcumin 
anyone knows please 🙏  OP 27 – Bharat B. Aggarwal (youtube.com)

James McCraw
Author Admin. From my book “Beating Cancer from the Grocery Store Revised”.
In 2012, MD Anderson launched a review of Aggarwal’s research after the federal government notified them of allegations of fraud by academic whistleblowers in as many as 65 of Aggarwal’s published papers, one of which had been retracted by the journal that published it.
Several more of Aggarwal’s publications were subsequently retracted after they were found to contain data images that had been reused and manipulated to represent different results.

Aggarwal resigned from his position at MD Anderson at the end of 2015.
By August 2016, eighteen research articles published by Aggarwal (in seven scientific journals) had been retracted.
I think the above ordeal was to discredit Doctor Aggarwal. The Cancer Industry (Big Pharma) is not going to sit back and let the Cancer Industry implode. There is a lot of money at stake and Aggarwal is telling people to watch their inflammation. He retired at the end of 2015. As of today, he is still fighting cancer and I am going 7 years in July 2020 being cancer free with a Glioblastoma Multiforme Grade 4 cancer.

Doctor Bharat B. Aggarwal PhD made a huge discovery when he was working at M.D. Anderson Cancer Clinic in Houston, Tx. He found out that most cancers were caused by inflammation. One would think that this discovery would be the end of cancer. Wrong, not so fast, this discovery was made in 2013-2014, it is now 2023 and Big Pharma is still trying to find a “cure” for cancer. What has happened since then? I think that the Cancer Industry which is worth a gazillion dollars tried to discredit Aggarwal for his findings and this led to the “war on cancer”.

The Cancer Industry is much stronger today than it was in 2014. He was big on Turmeric.
He found out that Curcumin which was 1-3% of Turmeric was the best cancer fighter around. Aggarwal explained that cancer is a chronic disease much like diabetes, arthritis, Alzheimer’s. He reasoned that the only way to fight cancer is through an anti-inflammatory lifestyle. He was regarded as a “quack” by his peers.

He said Turmeric has been around since the 1700’s fighting diseases.
In India, where he is from, if you had any kind of injury, you would put Turmeric on it. Why didn’t anyone believe him? Aggarwal said it comes down to dollars and cents. Turmeric is very cheap and how could anyone make money on something that was so plentiful. Turmeric Curcumin Alzheimer in India – Search (bing.com)
Aggarwal also said that chemotherapy and radiation would make the cancer metastasize. People do not die of the original tumor, they died because the cancer metastasized. He said that around 50 years ago Paul Ehrlich was the first one to use chemotherapy on humans. He wanted to try it on rats first to see how much to use on humans. Aggarwal said that this was the first time that other animals were used to fight a human disease.

Doctor Bharat B. Aggarwal saved my life.
I was diagnosed with a brain tumor, Glioblastoma Multiforme Grade 4, on July 22, 2013. My prognosis was 14 months. I haven’t done chemotherapy since May 5, 2014. If it wasn’t for the confidence given to me by Bharat, I would have done chemotherapy in December 2015 at my Oncologist suggestion. I refused. Beating Cancer | Facebook

https://youtu.be/8q9ZUWKs4tw?si=EiCQTK1l83wW3Obl

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Cancer Rates by Country 2024 (worldpopulationreview.com)
Cancer tends to be more prevalent in high-income countries due to lifestyle factors such
as smoking, obesity, and alcohol intake. Fortunately, these also tend to be countries with sound health care systems, which can better detect and treat cancer than the health-care systems in low-income countries. Moreover, advancements in medical knowledge and technology continue to improve each country’s cancer survival rate.
Although a decreasing percentage of cancer patients succumb to the disease, the total number of deaths from cancer continues to rise. This is often attributed to the fact that the world’s ever-growing population includes more senior citizens, whose cancer risk is highest, than ever before. Cancer rates are typically expressed as a crude rate or as an age-standardized rate, which adjusts for the fact that some countries’ populations are younger overall than others. Typically expressed as a crude rate or as an age-standardized rate, which adjusts for the fact that some countries’ populations are younger overall than others.

Top 10 Countries with the Highest Cancer Rates
(2020 Age-Standardized Rates per 100k, WHO).

Australia 452.4
New Zealand 422.9
Ireland 372.8
United States 362.2
Denmark 351.1
Netherlands 349.6
Belgium 349.2
Canada 348.0
France 341.9
Hungary 338.2

Stage IV Glioblastoma Multiforme
Brain Cancer Healed with Garlic and Curcumin (James McCraw) –
Cancer Compass an Alternate Route (cancercompassalternateroute.com)

Killing Cancer with Spices – Revised: Inflammation – Cancer Stem Cells:
McCraw Jr, James A, McCraw, James A: 9781793462787: Amazon.com: Books

Cancer Trilogy: My First Three Books: “Killing Cancer With Spices” “Cancer Stem Cells: Attacking Cancer From the Roots” “Cancer Stem Cells: If I Knew Then What I Know Now” – Kindle edition by McCraw, James. Health, Fitness & Dieting Kindle eBooks @ Amazon.com.

How to Starve Cancer and Boost Cancer-Killing Effects of Chemo with Curcumin (anticancer360.com)

Cancer Survivor, James McCraw – (templetonwellness.com)

Other Cancer Survivor Stories – (templetonwellness.com)

Killing Cancer With Spices Breakfast 1 (youtube.com)

Killing Cancer With Spices – Breakfast (youtube.com)

‘Cancer should have killed me in weeks – but turning down treatment for raw vegan diet has kept me alive for years’ – World News – Mirror Online

Tim McGraw Didn’t Meet His Dad Tug Until He Was 11. Inside Their Complicated Relationship (biography.com)
Surviving Multiple Myeloma for 29 Years – Conquer: the journey informed (conquer-magazine.com)
Anticancer Diet – Cancer Compass an Alternate Route (Cancer compass alternate route.com)
Einstein’s Quantum Riddle | Full Documentary | NOVA | PBS (youtube.com)
The Cannabis Question I Full Documentary I NOVA I PBS (youtube.com)
Where Did the Cannabis Plant Come From? (youtube.com)
Salicinium For Cancer – Arrow’s Newsletter (substack.com)

Search Results for Carl O Helvie | Cancer Quick Facts (solitarius.org) 

BONUS: Carl O’ Helvie Protocol – Search Videos (bing.com)

3000 mg of Laetrile until cancer is eradicated!!
Plus, Wobenzym N Reviews: Does It Really Effective?
Wobenzym N for Cancer – Search (bing.com)

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