The Sugar & Thiamine Connection

   It  has  been “hypothesized”  a Western Diet  characterized in part                    by excessive sugar consumption. Maybe a  factor for increased cancer incidences. Whereas,  in contrast t0 African countries that principally consume  foods high in thiamine  have reduced cancer rates.  It’s hard           to say  anyone nutrient lacking is the root cause when instead it takes             a natural balance (cancer is a survival mechanism not a disease?)

    Although no direct study has been evaluated, the dietary intake of  thiamine  and cancer risk have provided conflicting results. Thiamine        (or  Vitamin B1)  deficiencies have been  found in many sugar abusers,  which  causes  abnormally  slow oxidation  in  bodily  cells.  With  also  increased consumption of  sugar…. colds,  tonsillitis, sinus infections,    catarrhal disease and cancer is on the raise.

     People over time can become allergic to sugar,  producing internal       yeast over growth  and its toxic by-product  from consuming excessive  sugar causing allergies  and in some cases cancer.  Excessive sugar can change  the body’s biochemistry…. so the adrenal glands  are unable to   cope satisfactory with the toxic state of  being.

    While  in  a sugar glutton  when  (s)he  is exposed  to germs,  his/her  resistance is lowered and the Bacillus cell ( fungus) grows more rapidly       in his/her body.  It has long been known a good nutritious diet goes  far      in  helping  the  individual  recover  from  disease.  In  the  fore mention,  first paragraph,  before sugar can cause a thiamine deficiency which in turn leave your body exposed to all types of  health maladies.  

     A  2008  study,  examined  the  relationship  between  the  intake  of             B – vitamins and incidences of  breast, endometrial, ovarian, colorectal     and lung cancer in women.  Interestingly, reduced thiamine levels also increased  the number of  aberrant crypt  foci ( fungus) in the colons of      rats  fed  a sucrose – based diet.  Patients with severe malnutrition have exhibited Baker’s cyst, osteosarcoma and submandibular cyst.

  Which was cured without recurrence after thiamine administration,  which  suggest  a  role  of  thiamine  deficiency  in  tumor  development.           A limited number of studies and case reports have determined the over       all  status  in cancer patients.  Clinically,  thiamine status is quantified  biochemically using a TKT assay of  white blood samples.

   This assay…. which involves measuring the increase in the activity             of  the thiamine – dependent enzyme TKT after added TPP. If Deficient          in thiamine,  exogenous TPP  will stimulate TKT activity,  termed also         the TPP effect.  Similarly,  this increased TPP effect was characterized           in patients (B – Chronic Lymphocytic leukemia, Burkett’s Lymphoma,        and  Accute Myelomocytic Leukemia.)

    Although the reason  for a decrease in thiamine states in the blood               is unclear.  One study,  also noted cancer patients had a higher level of thiamine urinary excretion.  The authors of  this study suggest that the thiamine status might not be due to reduced dietary intake of thiamine,     but an inability to activate thiamine to TPP.

    This reduction  in peripheral thiamine/TPP  may be a consequence                of  extensive accumulation  and/or utilization  by cancer cells,  During tumor growth, cancer cells maintain a constant level of TPP,  while the     host  liver  tissue  exhibited a perpetual decline.  Overall,  these  studies strongly  suggest  a preferential accumulation of  thiamine  into cancer    cells. That may be responsible for the alteration in peripheral thiamine  status during malignancy.


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